Zourra Ingredient Clinical Evidence

A working bibliography of publicly available, peer-reviewed clinical studies for the key actives in each Zourra formula. Prioritises PubMed/PMC-indexed RCTs, systematic reviews and meta-analyses, journal sources, and regulatory (EFSA) assessments. Every link points to a published source. 

Compliance note. Clinical evidence for an ingredient is not the same as permission to make a claim. In GB, only claims on the Great Britain Nutrition and Health Claims (NHC) Register may be used. Authorised vitamin/mineral claims sit under retained EU Regulation 432/2012, built on EFSA NDA Panel opinions. Most botanical health claims remain ‘on hold’, so the studies below support formulation rationale and education, not necessarily on-pack claims. Treat this as a science dossier, not a claims list. 

 

  1. Focus Complex 

Saffron (Affron®) — mood, stress, focus 

Citicoline — attention & memory 

CoQ10 (ubiquinol) — cellular energy / fatigue 

B6, Zinc, K2, Selenium, D3 

These carry authorised EFSA/GB claims (e.g. B6, zinc and selenium contribute to normal cognitive/immune function; D3 and K2 to bone maintenance). Cite via the GB NHC Register rather than individual trials. 

 

  1. Magnesium Bisglycinate 

Magnesium’s contribution to normal psychological function, muscle function and reduction of tiredness/fatigue is an authorised claim — the strongest footing for messaging. 

 

  1. Vitality Complex 

Rhodiola rosea — stress-related fatigue 

Note: The review concluded the evidence is contradictory; individual RCTs are positive but heterogeneous. 

CoQ10 (upgrade ubiquinone → ubiquinol planned) 

Pomegranate extract — antioxidant / cardiovascular 

Iron bisglycinate — fatigue / iron status 

Vitamin C, B6 (P-5-P), Folate (5-MTHF), B12 

Authorised claims: each contributes to the reduction of tiredness and fatigue and normal energy-yielding metabolism; vitamin C also supports iron absorption and normal collagen formation. Cite via GB NHC Register. 

BioPerine® (piperine) 

Functions as a bioavailability enhancer, supports absorption of co-nutrients. 

 

  1. Harmony Complex 

Ashwagandha (KSM-66®) — stress & cortisol 

Sage (Salvia officinalis) — vasomotor symptoms 

Affron® Saffron — menopausal mood (most on-brand study) 

Note: This trial found significant benefit for mood/psychological symptoms. 

Red Clover — isoflavones / hot flushes 

Vitamin D3, B6, K2 

Authorised claims (bone, immune, hormonal/psychological function). Cite via GB NHC Register. 

 

  1. Desire Blend 

Ashwagandha (KSM-66®) — sexual function & stress 

Maca (Lepidium meyenii) — sexual function & menopausal symptoms 

Shatavari (Asparagus racemosus) — menopausal symptoms 

Red Clover, Zinc, B6 

Red clover as above. Zinc contributes to normal fertility/reproduction and testosterone levels (authorised). Cite via GB NHC Register. 

 

  1. Collagen Powder 

Hydrolysed collagen — skin elasticity, hydration, wrinkles 

Hyaluronic acid — skin hydration & wrinkles 

Vitamin C 

Authorised claim: contributes to normal collagen formation for skin function. This is the most defensible on-pack skin claim. Cite via GB NHC Register. 

 

Quick Credibility Summary 

Ingredient 

Evidence strength 

Best source type 

Saffron / Affron® (mood) 

Strong 

Multiple RCTs + meta-analysis 

Ashwagandha KSM-66® (stress) 

Strong 

Meta-analysis of 15 RCTs 

Sage (hot flushes) 

Moderate–strong 

RCTs + meta-analysis 

Citicoline (attention/memory) 

Strong 

RCTs + EFSA opinion 

CoQ10 (fatigue) 

Moderate–strong 

Meta-analysis 

Collagen (skin) 

Moderate (funding caveat) 

Meta-analyses 

Hyaluronic acid (skin) 

Moderate 

RCTs 

Red clover (hot flushes) 

Modest 

Meta-analyses 

Rhodiola (fatigue) 

Mixed 

RCTs + review 

Magnesium (sleep) 

Mixed; strong for fatigue claim 

Reviews + authorised claim 

Shatavari (menopause) 

Emerging 

Recent RCTs 

Maca (libido) 

Limited / suggestive 

Small RCTs 

Ginkgo (cognition) 

Weak in healthy adults 

Large null RCTs 

Iron bisglycinate (fatigue) 

Strong 

RCTs + authorised claim 

Vitamins / minerals 

Authorised claims 

EFSA / GB NHC Register 

Notes on scope. Where an ingredient relies on a vitamin/mineral, the regulatory-grade reference is the GB NHC Register rather than a single trial. For a formal substantiation file, pair each claim you intend to use with the specific authorised wording (vitamins/minerals) or hold the botanical evidence as education-only until claims are clarified.